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The generic name of CIPRO is ciprofloxacin hydrochloride Tablets and CIPRO (ciprofloxacin*) Oral Suspension are synthetic broad spectrum antimicrobial agents for oral administration. It is a faintly yellowish to light yellow crystalline substance with a molecular weight of 385.8 and its empirical formula is C17H18FN3O3-HCl-H2O. CIPRO film-coated tablets are available in 250 mg, 500 mg and 750 mg tablet. Ciprofloxacin tablets are white to slightly yellowish in color. The inactive ingredients are cornstarch, titanium dioxide, microcrystalline cellulose, silicon dioxide, crospovidone, magnesium stearate, hypromellose, and polyethylene glycol.
Ciprofloxacin Oral Suspension is available in (5 g ciprofloxacin in 100 mL) and (10 g ciprofloxacin in 100 mL) strengths. Ciprofloxacin Oral Suspension is a white to slightly yellowish suspension with strawberry flavor and may contain yellow-orange droplets. It is composed of ciprofloxacin microcapsules and diluent which are mixed prior to dispensing and the components of the suspension have the following compositions:
Microcapsules-ciprofloxacin, povidone, hypromellose, magnesium stearate, methacrylic acid copolymer, and Polysorbate 20. Diluent-medium-chain triglycerides, lecithin, sucrose, water, and strawberry flavor.
CIPRO is indicated for the treatment of infections caused by susceptible strains of the designated microorganisms in the conditions that are listed below:
Urinary Tract Infections caused by Escherichia coli, Klebsiella pneumoniae, Staphylococcus saprophyticus, Enterobacter cloacae, Serratia marcescens, Proteus mirabilis, Providencia rettgeri, Morganella morganii, Citrobacter diversus, Citrobacter freundii, Pseudomonas aeruginosa, methicillin-susceptible Staphylococcus epidermidis, or Enterococcus faecalis.
Acute Uncomplicated Cystitis in females caused by Escherichia coli and Staphylococcus saprophyticus.
Chronic Bacterial Prostatitis caused by Escherichia coli and Proteus mirabilis. Lower Respiratory Tract Infections caused by Pseudomonas aeruginosa Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, Proteus mirabilis, Haemophilus influenzae, Haemophilus parainfluenzae, or penicillin-susceptible Streptococcus pneumoniae. Although effective in clinical trials, ciprofloxacin is not a drug of choice in the treatment of presumed or confirmed pneumonia secondary to Streptococcus pneumoniae.
Acute Sinusitis caused by Haemophilus influenzae, Moraxella catarrhalis and penicillin-susceptible Streptococcus pneumoniae.